Is it a good idea to set an I/O setting on game mode? How to

Here is my configuration file:

Is there a way to set "Best effort" for I/O or if advisable "Realtime" in this file? like in KsysGuard?

cat /etc/security/limits.d/10-gamemode.conf
File: /etc/security/limits.d/10-gamemode.conf
@gamemode - nice -10